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Biomedical Engineering related Diagnostic Research Laboratory 

​분자진단 의공학 연구실

Department of Biotechnology

​College of Life Science and Biotechnology

Yonsei University

RESEARCH Fields

- Molecular diagnostics

- Sample preparation platform

- Detection platform

- Point-of-care Testing platform

- Treatment using biomaterials

Research Interests

  • Development of Medical Diagnostic Applications and Devices to early detection of Human diseases using Biophotonic Device (Neurological diseases and Cancer, and infectious diseases)

  • Development of novel DNA amplification techniques (iNAD; Isothermal Solid phase Nucleic Acids Amplification/Detection) in field of POC (point-of-care) based clinical applications 

  • Development of novel sample processing techniques (SLIM; homobifunctional imidoesters/thin film) in field of POC (point-of-care) based clinical applications 

  • Identification and characterization of DNA Biomarkers (Neurological diseas, Cancer, Infectious)

  • Identification of Cells, Proteins or Nucleic acids (Genetic; DNA/RNA, and Epigenetic; miRNAs, DNA methylation) from Human Fluidics (Blood, Urine, CSF and so on)

  • Drug Delivery System & Antifungal agents using Nanomaterials

Contact

Selected
Publications

"Biporous Silica Nanofilm with High Surface Area and Dynamic Flow: Enrichment and Isolation of SARS-CoV-2 RNAs towards PCR-free Detection" Nature Communications (IF 17.7). 15(1), 1366. 2024 

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“Deep learning assisted ZnO-Au-SERS system for rapid and direct nucleic acid amplification and detection: toward enhanced molecular diagnostics" ACS Nano (IF 17.1). 17, 18332-18345, 2023

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"Recent advances in extracellular vesicle-based organic nanotherapeutic drugs for precision cancer therapy" Coordination Chemistry Reviews (IF 24.8). 479, 215006. 2023

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“Chimeric nanocomposites for the rapid and simple isolation of urinary extracellular vesicles” Journal of Extracellular Vesicles (IF 25.841). e12195, 2022

“Trends and Challenges of Nanotechnology in Self-test at Home” Trends in Analytical Chemistry (IF. 14.29). 144, 116428, 2021.

“Gene-based diagnosis of tuberculosis with a new generation pathogen enrichment technique” European Respiratory Journal (IF. 33.8). 55, 1901885, 2020. 

“Simple and low-cost sampling of cell-free nucleic acids from liquid biopsy of cancer patients” Advanced Science (IF. 17.8). 10, 100614. 2018.

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